By J. Michael Dixon
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Extra resources for ABC of Breast Diseases, 3rd edition (ABC Series)
Dixon JM. Repeated aspiration of breast abscesses in lactating women. Br Med J 1988;297:1517–18. ● Dixon JM, RaviSekar O, Chetty O, Anderson TJ. Periductal mastitis and duct ectasia: different conditions with different aetiologies. Br J Surg 1996;83:820–22. ● Hughes LE, Mansel RE, Webster DJT. Benign disorders and diseases of the breast: concepts and clinical management. 2nd ed. London: Saunders, 2000. ● Dixon JM, Bundred NJ. Management of disorders of the ductal system. In: Harris JR, Lippman ME, Morrow M, Hellman S, eds.
Taylor GB, Paviour SD, Musaad S, Jones WO, Holland DJ. A clinicopathological review of 34 cases of inflammatory breast disease showing an association between corynebacteria infection and granulomatous mastitis. Pathology 2003;35:109–19. ● 23 5 Breast cancer—epidemiology, risk factors, and genetics K McPherson, CM Steel, JM Dixon With over a million new cases in the world each year, breast cancer is the most common malignancy in women and comprises 18% of all female cancers. Age standardised incidence and mortality in the United Kingdom are among the highest in the world.
160 Placebo Tamoxifen 120 80 40 Prevention of breast cancer Screening as currently practiced can reduce mortality but not incidence and is cost effective only among women in whom breast cancer is common (Ͼ2/1000 per year). Advances in treatment—hormonal and cytotoxic—and better delivery of care have also produced considerable survival benefits. A greater appreciation of factors important in the aetiology of breast cancer would raise the possibility of disease prevention. 0 Total 35–49 50–59 60+ Age group (years) The effect of tamoxifen on the incidence of breast cancer according to age (Data from the NSABP prevention study) One promising avenue for primary prevention is influencing the hormonal milieu of women at risk.
ABC of Breast Diseases, 3rd edition (ABC Series) by J. Michael Dixon