ABC Proteins. From Bacteria to Man by I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher PDF

By I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher F. Higgins

ISBN-10: 0123525519

ISBN-13: 9780123525512

  • ''...the quantity surely succeeds total as an in-depth survey of either the biology and the biochemistry of a ubiquitous and astonishingly different kin of very advanced enzymes. each team with an curiosity in those proteins should still personal a copy.'' -CELL (July 2003) ''The editors of ABC Proteins: From micro organism to Man have valiantly tried to surround during this quantity the complete scope of analysis on those proteins, from atomic-resolution constitution to human genetic illnesses, and from Escherichia coli to Homo sapiens and Arabidopsis thaliana... What the ebook makes visible is that almost all ABC proteins are membrane localized, ATP based, fundamental energetic transporters...In addition to advances in our knowing of ABC transporter constitution, numerous chapters within the booklet additionally describe growth that has been made in elcuidating the mechanisms of delivery. the quantity undoubtedly succeeds total as an in-depth survey of either the biology and the biochemistry of a ubiquitous and astoundingly different kinfolk of very advanced enzymes. each workforce with an curiosity in those proteins should still personal a duplicate. ultimately, this booklet makes a resounding case that many laboratories that will not but suspect it is going to quickly have a way more abiding curiosity in ABC proteins.'' ''...well prepared and integrated superbly transparent colour photos and figures.'' -E STREAMS (July 2003)

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2001) Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing. EMBO J. 20, 4964–4972. S. G. (2001) ABC transporters associated with cytochrome c biogenesis. Res. Microbiol. 152, 323–329. K. G. (1996) Use of heme reporters for studies of cytochrome biosynthesis and heme transport. J. Bacteriol. 178, 6338–6347. Goosen, N. F. (2001) Role of ATP hydrolysis by UvrA and UvrB during nucleotide excision repair. Res. Microbiol. 152, 401–409. , Chimini, G. and Kuipers, F.

2001) ABC transporters associated with cytochrome c biogenesis. Res. Microbiol. 152, 323–329. K. G. (1996) Use of heme reporters for studies of cytochrome biosynthesis and heme transport. J. Bacteriol. 178, 6338–6347. Goosen, N. F. (2001) Role of ATP hydrolysis by UvrA and UvrB during nucleotide excision repair. Res. Microbiol. 152, 401–409. , Chimini, G. and Kuipers, F. (2001) Hepatobiliary cholesterol transport as not impaired in Abca1-null mice lacking HDL. J. Clin. Invest. 108, 843–850. G.

Apart from the MCM family, which is found only in methanogenic archaea, and the PDR subfamily, which is found only in plants and fungi, most families have been identified in more than one kingdom. CONCLUSIONS AND PERSPECTIVES 1. Each of the three classes of ABC systems contains proteins from the three kingdoms: archaea, bacteria and eukaryotes. The separation of eukaryotic from prokaryotic systems does not occur at the root of the clusters. Homologous systems from the three kingdoms are present at the tip of the branches of the tree.

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ABC Proteins. From Bacteria to Man by I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher F. Higgins


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