Read e-book online Advances in Immunology, Vol. 95 PDF

By Frederick W. Alt (ed.), K. Frank Austen (ed.), Tasuku Honjo (ed.), Fritz Melchers (ed.), Jonathan W. Uhr (ed.), Emil R. Unanue (ed.)

ISBN-10: 0123737087

ISBN-13: 9780123737083

Advances in Immunology, a protracted demonstrated and hugely revered book, provides present advancements in addition to entire reports in immunology. Articles deal with the big variety of subject matters that include immunology, together with molecular and mobile activation mechanisms, phylogeny and molecular evolution, and scientific modalities. Edited and authored via the most important scientists within the box, each one quantity offers up to date details and instructions for destiny study.

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Extra resources for Advances in Immunology, Vol. 95

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In these cases, it was concluded that immature B cells can function as antigen-presenting cells to T-cell lines. 2) expression. This costimulatory molecule is important in the productive interaction between antigen-reactive B and T cells. , 2000). TCR binding of class II: peptide complexes on the antigen-presenting cell (signal 1), without concurrent ligation of CD28 with CD80 or CD86 (signal 2), has been shown to lead to anergy in the responding naive T cells (Schwartz, 2003). On the other hand, activated T lymphocytes are not as dependent on costimulation by the antigen-presenting cell, in this case, the B lymphocyte.

1987). Development of the primary antibody repertoire. Science 238, 1079–1087. Amanna, I. , Dingwall, J. , and Hayes, C. E. (2003). Enforced bcl-xL gene expression restored splenic B lymphocyte development in BAFF-R mutant mice. J. Immunol. 170, 4593–4600. , Rand, M. , and Lake, R. J. (1999). Notch signaling: Cell fate control and signal integration in development. Science 284, 770–776. , Maandag, E. , Izon, D. , Kruisbeek, A. , Weintraub, B. , Schlissel, M. , Feeney, A. , te Riele, H. P. , et al.

G. (2003). Incomplete activation of CD4 T cells by antigen-presenting transitional immature B cells: Implications for peripheral B and T cell responsiveness. J. Immunol. 171, 1758–1767. Cobb, B. , and Smale, S. T. (2005). Ikaros-family proteins: In search of molecular functions during lymphocyte development. Curr. Top. Microbiol. Immunol. 290, 29–47. Corcoran, A. , and Venkitaraman, A. R. (1998). Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor. Nature 391, 904–907. Dal Porto, J.

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Advances in Immunology, Vol. 95 by Frederick W. Alt (ed.), K. Frank Austen (ed.), Tasuku Honjo (ed.), Fritz Melchers (ed.), Jonathan W. Uhr (ed.), Emil R. Unanue (ed.)

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